Diffusion Tensor Imaging of Epileptogenic Lesions in TSC.
نویسندگان
چکیده
Investigators from University of California Los Angeles, studied whether epileptogenic tubers in Tuberous Sclerosis Complex (TSC) can be identified by diffusion tensor imaging (DTI).
منابع مشابه
DTI of tuber and perituberal tissue can predict epileptogenicity in tuberous sclerosis complex.
OBJECTIVE To evaluate whether diffusion tensor imaging (DTI) can predict epileptogenic tubers by measuring apparent diffusion coefficient (ADC), fractional anisotropy, axial diffusivity, and radial diffusivity in both tubers and perituberal tissue in pediatric patients with tuberous sclerosis complex (TSC) undergoing epilepsy surgery. METHODS We retrospectively selected 23 consecutive patient...
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Tuberous sclerosis complex (TSC) is a rare disorder of tissue growth and differentiation, characterized by benign hamartomas in the brain and other organs. Up to 90% of TSC patients develop epilepsy and 50% become medically intractable requiring resective surgery. The surgical outcome of TSC patients depends on the accurate identification of the epileptogenic zone consisting of tubers and the s...
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PURPOSE About one-third of patients with epilepsy are refractory to medical treatment and may be amenable to surgery. However, in patients with lesions on or near the presumed course of the optic radiation, the potential benefits of resection must be balanced against the risk of a visual field deficit. This study demonstrates the utility of diffusion tensor imaging (DTI) tractography in delinea...
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BACKGROUND AND PURPOSE Although patients with tuberous sclerosis complex (TSC) manifest various structural abnormalities, we hypothesized that white matter (WM) structures that appear normal on conventional MR imaging may be accompanied by microstructural changes, such as gliosis and myelinization defects. Our objective was to determine in vivo whether there was evidence for WM microstructural ...
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TAPANI TIKKAKOSKI Editor In patients with intractable epilepsy refractory to medication, surgical treatment may be needed. Magnetic resonance imaging (MRI) is an essential neuroimaging tool in assisting the identifi cation of epileptogenic lesions. MRI at 3T has been found to perform better than 1.5T in terms of image quality, detection of structural lesions, and characterization of lesions. Th...
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ورودعنوان ژورنال:
- Pediatric neurology briefs
دوره 30 2 شماره
صفحات -
تاریخ انتشار 2016